Table 3

 Sleep parameters taken from the Pittsburgh sleep quality index (PSQI) and the Epworth sleepiness scale (ESS) before and after two weeks of treatment

ParameterBefore melatonin treatment (absolute baseline score)After melatonin treatment (decrease in score)
MelatoninPlaceboMelatoninPlacebo
All data are geometric mean (SEM).
There were no significant differences between the melatonin and placebo groups for any of the absolute baseline scores or after two weeks of treatment.
Global PSQI score7.50 (0.78)6.45 (0.58)2.25 (0.45)2.15 (0.53)
    Sleep quality1.25 (0.17)1.10 (0.18)0.35 (0.15)0.25 (0.12)
    Sleep latency1.60 (0.28)1.35 (0.21)0.55 (0.18)0.70 (0.18)
    Sleep duration1.60 (0.23)1.40 (0.67)0.65 (0.20)0.90 (0.07)
    Habitual sleep efficiency0.25 (0.12)0.15 (0.05)0.20 (0.14)0.00 (0.07)
    Sleep disturbance1.40 (0.13)1.25 (0.11)0.05 (0.17)0.30 (0.13)
    Use of sleep altering medications0.20 (0.17)0.15 (0.11)0.20 (0.17)0.15 (0.11)
    Daytime dysfunction1.20 (0.27)1.05 (0.20)0.15 (0.22)0.45 (0.26)
ESS score10.05 (0.72)9.75 (0.77)1.65 (0.92)1.80 (0.76)