Circulating vitamin D metabolites and parathyroid hormone balance in adult patients with inflammatory bowel disease
| 1,25(OH)2D (pg/ml) | 25(OH)D (ng/ml) | iPTH (pg/ml) | |
|---|---|---|---|
| CD, Crohn’s disease; UC, ulcerative colitis; 1,25(OH)2D, 1,25-dihydroxyvitamin D; 25(OH)D, 25-hydroxyvitamin D; iPTH, immunoreactive parathyroid hormone. | |||
| Normal (n = 96) | |||
| Mean (SEM) | 42.1 (1.4) | 27.0 (0.8) | 32.3 (0.8) |
| Median | 41.5 | 26 | 29 |
| Range | 15–85 | 5–57 | 11–74 |
| CD (n = 138) | |||
| Mean (SEM) | 57.8 (2.5) | 24.2 (1.2) | 32.6 (2.4) |
| Median | 54 | 25.5 | 28.5 |
| Range | 24–233 | 9–66 | 10.6–73 |
| UC (n = 29) | |||
| Mean (SEM) | 41.3 (2.8) | 25.9 (3.3) | 28.8 (7.9) |
| Median | 42 | 30 | 24.8 |
| Range | 18–72 | 7–48 | 10–72 |
| t test (p values) | |||
| Normal v CD | <0.0001 | 0.35 | 0.45 |
| Normal v UC | 0.31 | 0.06 | 0.19 |
| CD v UC | 0.0001 | 0.12 | 0.28 |