Table 7

Helicobacter pylori eradication with triple therapy (proton pump inhibitor-amoxicillin-metronidazole) according to susceptibility or resistance to metronidazole

ReferenceType of treatmentEradication rate
OverallMetronidazole susceptibleMetronidazole resistant
*Second line H pylori eradication treatment.
O, omeprazole; P, pantoprazole; R, rabeprazole; M, metronidazole; A, amoxicillin.
Bardhan120OAM 1 week81.5% (274/336)87% (233/266)57% (41/70)
Bayerdorffer121OAM 1 week88% (96/109)91% (81/89)75% (15/20)
Isomoto122*RAM 2 weeks91.6% (33/36)93% (27/29)86% (6/7)
Lamouliatte102*OAM 2 weeks69.8% (67/96)81% (38/47)59% (29/49)
Murakami123*RAM 1 week92.9% (79/85)96.8% (61/63)81.8% (18/22)
Pilotto109PAM 1 week85.2% (29/34)96% (24/25)56% (5/9)
Total83% (578/696)89.4% (464/519)64.4% (114/177)