Table 1

 Effect of leptin on cytokine production in RBhigh and RBlow cells

IL-6 (pg/ml)IL-10 (pg/ml)
RBhigh and RBlow cells were prepared as described in materials and methods and stimulated overnight with anti-CD3 and anti-CD28, in the presence or absence of leptin. Cytokine levels (interleukin (IL)-6 and IL-10) were below detection limits in cells cultured in the absence of anti-CD3 and anti-CD28, with or without leptin.
Data are mean (SEM); n = 3. *p<0.05, **p<0.01 versus respective no leptin.
RBhigh–no leptin148.1 (22.7)249.5 (22.2)
RBhigh–with leptin78.5 (32.1)*<10**
RBlow–no leptin42.4 (34.6)427.7 (15.7)
RBlow–with leptin29.9 (24.4)354.4 (52.2)