PSC-IBD versus UC
| Clinical parameter | PSC-IBD (n (%)) | UC (n (%)) | p Value (OR (CI)) |
|---|---|---|---|
| PSC, primary sclerosing cholangitis; IBD, inflammatory bowel disease; UC, ulcerative colitis; OR, odds ratio; CI, confidence interval. | |||
| *Excluded from this row, four patients with pure ileal PSC and three patients with incomplete colonic site data. | |||
| †p adjusted for extensive colitis; p = 0.10 for univariate analysis of immunosuppression versus patient group; p = 0.009 for immunosuppression and extensive colitis adjusted for patient group, OR = 2.0 (CI 1.2–3.4). | |||
| ‡All 16 cancer/high grade dysplasia patients had extensive disease (p<0.0001). | |||
| Extensive colitis* | |||
| No | 1 | 172 | <0.0001 |
| Yes | 70 (99) | 121 (41) | 100 (14–727) |
| Immunosuppression | |||
| No | 64 | 218 | 0.007† |
| Yes | 13 (17) | 76 (26) | 0.36 (0.17–0.77) |
| Colectomy | |||
| No | 53 | 223 | 0.14 |
| Yes | 25 (32) | 71 (24) | |
| High grade dysplasia | 3 | 5 | |
| Colon cancer | 4 | 4 | |
| Total | 7 (9) | 9 (1.4) | 0.029‡ |
| 3.6 (1.3–10.2) | |||