Clinical behaviour in ulcerative colitis patients by prior appendicectomy
| Clinical parameter | App+ (n (%)) | App− (n (%)) | p Value | OR (95% CI) |
|---|---|---|---|---|
| App+, prior appendicectomy; App−, no appendicectomy prior to diagnosis. | ||||
| *p value adjusted for disease extent, multivariate analysis. | ||||
| †Multivariate analysis (odds ratio (OR); confidence interval (CI)). | ||||
| Immunosuppression versus appendicectomy, univariate OR = 0.15 (CI 0.02–1.15), p = 0.052. Immunosuppression correlated independently with disease extent, p = 0.008, OR = 2.1 (CI 1.2–3.5). | ||||
| Extensive colitis | ||||
| No | 8 | 164 | 0.13 | |
| Yes | 11 (58) | 110 (40) | ||
| Immunosuppression | ||||
| No | 18 | 201 | 0.049* | 0.13† |
| Yes | 1 (5.6) | 74 (27) | (0.02–0.99) | |
| Colectomy for severe disease | ||||
| No | 16 | 201 | 0.08 | 5.3 |
| Yes | 1 (5.9) | 67 (25) | (0.69–41) | |
| Immunosuppression or colectomy for severe disease | ||||
| No | 16 | 161 | 0.004 | 0.09 |
| Yes | 1 (5.9) | 107 (40) | (0.01–0.72) | |
| All colectomy | ||||
| No | 16 | 207 | 0.58 | |
| Yes | 3 (16) | 68 (25) | ||
| Colectomy for: | ||||
| High grade dysplasia | 0 | 5 | ||
| Colorectal cancer | 2 | 2 | ||
| Total | 2 (11) | 7 (2.5) | 0.11 | |