Cumulative characteristics of the five consecutive chronologic cohorts of patients seen in our unit within the three months following diagnosis (group 1)
| Cohort 1978–82 | Cohort 1983–87 | Cohort 1988–92 | Cohort 1993–97 | Cohort 1998–2003 | |
|---|---|---|---|---|---|
| Numbers in parentheses are percentages. | |||||
| IS, immunosuppressants. | |||||
| Patients (n) | 34 | 46 | 102 | 176 | 207 |
| Deceased | 4 | 2 | 3 | 3 | 0 |
| Lost to follow up | 14 (41) | 20 (43) | 42 (41) | 70 (40) | 24 (12) |
| Median disease duration, months (interquartile range) | 188 (23–256) | 181 (64–207) | 123 (43–144) | 59 (10–91) | 14 (3–35) |
| Vienna classification | |||||
| Inflammatory | 15 (44) | 17 (37) | 42 (41) | 95 (54) | 130 (63) |
| Stricturing | 9 (26) | 4 (9) | 17 (17) | 22 (13) | 11 (5) |
| Penetrating | 10 (29) | 25 (54) | 43 (42) | 59 (34) | 66 (32) |
| Medical treatment | |||||
| No steroids, no IS | 6 (18) | 7 (15) | 20 (20) | 57 (32) | 60 (29) |
| Steroids, no IS | 22 (65) | 29 (63) | 51 (50) | 80 (45) | 81 (39) |
| IS | 6 (18) | 10 (22) | 31 (30) | 39 (22) | 66 (32) |
| Early withdrawal of IS | 0 | 1 (2) | 2 (2) | 1 (1) | 4 (2) |
| Infliximab | 0 | 1 (2) | 1 (1) | 7 (4) | 13 (6) |
| Cumulative number of intestinal resections | |||||
| 0 | 18 (53) | 23 (50) | 53 (52) | 120 (68) | 161 (78) |
| 1 | 11 (32) | 17 (37) | 42 (41) | 50 (28) | 45 (22) |
| 2 | 2 (6) | 5 (11) | 5 (5) | 6 (3) | 1 |
| >2 | 3 (9) | 1 (2) | 2 (2) | 0 | 0 |