Table 2

 IL-8 levels in tissues of FABP-rtTA × TRE2IL-8 mice after DOX induction*

Tissueng IL-8 per mg total proteinInduction ratio†
*Tissues were harvested from untreated FABP-rtTA × TRE2IL-8 mice or double transgenic mice that were given DOX in drinking water for 72 hours. The IL-8 content of the homogenised tissue was determined by ELISA and normalised to the total protein concentration. The IL-8 values from the DOX-induced mice are shown.
†Ratio of normalised IL-8 concentration in DOX-induced FABP-rtTA × TRE2IL-8 mice to uninduced double transgenic mice.
Ileum6.430.8
Caecum12.361.7
Proximal colon2.911.0
Kidney0.22.0
Lung0.31.8