Anthropomorphic and clinical characteristics of all study patients
| NASH (n = 13) | Controls (n = 9) | p Value | |
|---|---|---|---|
| NASH, non-alcoholic steatohepatitis; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γ-GT, gamma glutamyl transferase; HOMA, homeostasis model assessment. | |||
| Grade of steatosis, fibrosis, and inflammation were histologically verified and classified as: grade 1, no; grade 2, light; grade 3, mild; and grade 4, severe. | |||
| Values are means (SEM). | |||
| Age (y) | 44 (3.1) | 34 (4.3) | NS |
| Sex (F/M) | 9/4 | 7/2 | NS |
| BMI (kg/m2) | 45.59 (1.37) | 47.90 (2.69) | NS |
| AST (U/l) | 26.75 (4.26) | 21.44 (1.86) | NS |
| ALT (U/l) | 41.17 (8.67) | 23.44 (1.59) | NS |
| γ-GT (U/l) | 49.83 (7.71) | 27.62 (10.84) | NS |
| HOMA index | 2.32 (0.61) | 2.34 (0.87) | NS |
| Adiponectin (μg/ml) | 5.38 (0.92) | 6.86 (1.15) | NS |
| Grade of steatosis (1–4) | 1.46 (0.24) | 1.22 (0.22) | NS |
| Grade of fibrosis (1–4) | 1.85 (0.25) | 1.00 (0) | <0.01 |
| Grade of inflammation (1–4) | 1.92 (0.21) | 1.00 (0) | <0.01 |