Differential gene expression in Budd-Chiari syndrome (acute or chronic BCS) versus normal liver
| Gene | Acute BCS | Chronic BCS | ||
|---|---|---|---|---|
| Mean (SD) | p Value | Mean (SD) | p Value | |
| COL1A1 | 7.5 (1.1) | <0.0001 | 10.9 (5.2) | 0.04 |
| ANGPT1 | 5.8 (0.8) | <0.0001 | 7.9 (2.0) | 0.0009 |
| COL4A1 | 4.8 (0.7) | <0.0001 | 6.7 (2.4) | 0.01 |
| MMP2 | 4.1 (0.8) | 0.001 | 6.9 (2.0) | 0.003 |
| PDGFRB | 3.3 (0.8) | 0.007 | 4.8 (1.5) | 0.009 |
| PLAT | 4.9 (1.4) | 0.008 | 5.2 (1.3) | 0.001 |
| CTGF | 11.4 (2.6) | 0.0004 | 6.9 (2.8) | 0.02 |
| PDGFA | 3.3 (0.8) | 0.007 | 4.9 (0.9) | 0.0003 |
| PDGFRA | 4.1 (0.5) | <0.0001 | 8.5 (3.4) | 0.02 |
| PLAU | 4.8 (1.6) | 0.02 | 3.8 (1.2) | 0.02 |
| F3 | 6.8 (1.1) | <0.0001 | 8.0 (4.0) | 0.05 |
| PDGFB | 2.5 (0.4) | 0.003 | 3.3 (1.3) | 0.05 |
| IL6 | 4.3 (1.5) | 0.03 | 2.8 (2.4) | NS |
| VEGFC | 3.1 (0.9) | 0.02 | 1.0 (0.3) | NS |
| THBS1 | 3.1 (0.7) | 0.005 | 1.2 (0.4) | NS |
| ANGPT2 | 2.6 (0.5) | 0.007 | 4.6 (3) | NS |
| THBD | 2.2 (0.5) | 0.03 | 1.3 (0.3) | NS |
| SCG10 | 2.9 (1.3) | NS | 25.1 (7.0) | 0.0009 |
| MMP7 | 1.2 (0.3) | NS | 5.1 (0.9) | 0.001 |