Characteristics of hereditary non-polyposis colorectal cancers and frequency of pathogenic β-catenin mutations
| Site | Stage | Grade* | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Proximal | Distal | A | B | C | D | Well | Mod | Poor | |
| *Grade defined as well, moderate, and poorly differentiated. | |||||||||
| Total | 17 | 18 | 7 | 18 | 9 | 2 | 2 | 28 | 8 |
| No of mutations | 4 | 3 | 1 | 0 | 4 | 2 | 0 | 6 | 1 |
| % | 23.5 | 16.7 | 14.2 | 0 | 44.4 | 100 | 0 | 21.4 | 12.5 |