Table 2

 Results from separate multiple logistic regression analyses examining the risk of HCC (v non-cancer controls) with each of diabetes, HCV, HBV, alcoholic liver disease, and haemochromatosis

Adjusted OR95% CIp Value
HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus; OR, odds ratio; 95% CI, 95% confidence interval.
All models adjusted for age, sex, race, SEER registry, and Medicare/Medicaid dual enrolment (n = 8244).
Interaction terms between HBV and diabetes, alcoholic liver disease and diabetes, and haemochromatosis and diabetes were not significant at a p value of <0.05.
Diabetes3.082.74–3.46<0.0001
    Excluding HCV (n = 7758)2.992.64–3.40<0.0001
    Excluding HBV (n = 8048)3.112.76–3.50<0.0001
    Excluding alcoholic liver disease (n = 7769)2.942.59–3.34<0.0001
    Excluding haemochromatosis (n = 8156)3.082.73–3.47<0.0001
    Excluding patients without any of the above risk factors (n = 7042)2.872.49–3.30<0.0001
HCV without diabetes24.4217.49–34.11<0.0001
HCV and diabetes36.882.64–3.40<0.0001
HBV23.9413.65–41.99<0.0001
Alcohol liver disease69.6244.92–107.90<0.0001
Haemochromatosis8.885.24–15.07<0.0001