Table 4

 Sixteen genes differentially expressed more than threefold (p<0.05), comparing Dukes’ B and C adenocarcinomas of the caecum with those of the sigmoid or rectosigmoid

Probe set IDGene nameSymbolUG clusterCyto bandDukes’ BDukes’ C
Bcae med*Bsig med†Avg FC Bcae v Bsig‡Ccae med§Csig med¶Avg FC Ccae v Csig
*Bcae med, median derived from “signal” of five Dukes’ B adenocarcinomas of the caecum.
†Bsig med, median derived from “signal” of eight Dukes’ B adenocarcinomas of the sigmoid and rectosigmoid.
‡FC, fold change, corresponding to the “signal ratio”, was calculated from the “signal log ratio”.
§Ccae med, median derived from “signal” of five Dukes’ C adenocarcinomas of the caecum.
¶Csig med, median derived from “signal” of seven Dukes’ C adenocarcinomas of the sigmoid and rectosigmoid.
UG cluster, UniGene cluster (http://www.ncbi.nlm.nih.gov/UniGene).
D00654_atEnteric smooth muscle gamma-actin geneACTG2Hs.780452p1388164−2.787465−5.6
D13643_at24-dehydrocholesterol reductaseDHCR24Hs.756161p33–p31.14533771.45031973.2
D17408_s_atCalponin 1, basic, smooth muscleCNN1Hs.2122319p13.2–p13.147105−2.779281−4.5
D90279_s_atCollagen, type V, alpha 1COL5A1Hs.1464289q34.2–q34.337−1.621158−4.1
HG2743-HT2846_s_atCaldesmon 1 Alt. Splice 6 Non-Muscle (M64110)CALD1Hs.3254747q334288−2.257306−4.4
HG2743-HT3926_s_atGamma-glutamyltransferase 1 (J04131)GGT1Hs.28438022q11.1–q11.21029−2.93096−4.4
M26679_atHomeo box A5HOXA5Hs.370347p15–p1430171.859153.4
M58459_atRibosomal protein S4, Y-linkedRPS4YHs.180911Yp11.36157−8.89560−23.3
M83216_s_atCaldesmon 1CALD1Hs.2862387q3327106−2.884466−4.2
M84526_atD component of complement (adipsin)DFHs.15559719p13.3249742.039112−5.4
M95787_atTransgelin 11 (SM22-alpha)TAGLNHs.7577711q23.2360663−2.05423600−5.3
U28368_atInhibitor of DNA binding 4ID4Hs.348536p22–p21416−2.0438−5.4
U35139_atNecdin (mouse) homologNDNHs.5013015q11.2–q122333−1.6958−5.7
U48959_atMyosin, light polypeptide kinaseMYLKHs.2115823q2183168−2.3146618−5.8
U52191_s_atSMC (mouse) homolog, Y chromosomeSMCYHs.80358Yq11215−4.6248−12.2
X51405_atCarboxypeptidase E (EC 3.4.17.10)CPEHs.753604q32.31022−2.51346−4.1