Incidence and relative risk of oesophageal squamous cell carcinoma during 1987–2001, by initial histological diagnosis
| 1987 diagnosis | No of subjects | No of OSCC cases | Cumulative OSCC incidence (%) | OSCC incidence rate* | Relative risk (95% CI) of OSCC incidence† |
|---|---|---|---|---|---|
| BCH, basal cell hyperplasia; mD, mild dysplasia; MD, moderate dysplasia; SD, severe dysplasia; NOS, dysplasia not otherwise specified; CIS, carcinoma in situ; OSCC, oesophageal squamous cell carcinoma. | |||||
| *Oesophageal cancer incidence rates (per 100 000 person years) adjusted to the age distribution of the analytic cohort at baseline (<50 years = 22.4%; 50–59 years = 46.0%; ⩾60 years = 31.5%). | |||||
| †Relative risk (95% confidence interval (CI)) for OSCC adjusted for age, sex, tobacco use, alcohol use, 1983 cytology diagnosis, and treatment group. | |||||
| Normal | 375 | 31 | 8.3 | 605 | 1.0 (ref) |
| Acanthosis | 77 | 6 | 7.8 | 597 | 0.9 (0.4–2.2) |
| BCH | 40 | 6 | 15.0 | 1637 | 1.9 (0.8–4.5) |
| Oesophagitis | 33 | 2 | 6.1 | 493 | 0.8 (0.2–3.2) |
| mD | 76 | 18 | 23.7 | 1518 | 2.9 (1.6–5.2) |
| MD | 30 | 15 | 50.0 | 10507 | 9.8 (5.3–18.3) |
| SD | 23 | 17 | 73.9 | 21364 | 28.3 (15.3–52.3) |
| NOS | 12 | 7 | 58.3 | 7689 | 12.7 (5.5–29.6) |
| CIS | 16 | 12 | 75.0 | 21194 | 34.4 (16.6–71.4) |
| Total | 682 | 114 | 16.7 | 1510 | na |