Table 1

 Number of patients studied and Toll-like receptor 4 Asp299Gly allele and genotype frequencies in Crohn’s disease (CD), ulcerative colitis (UC), and healthy control (HC) populations from Leuven, Munich, and Edinburgh

Patient numbers (allele frequencies)Crohn’s disease genotype frequencies
HC allele frequencies differed between Edinburgh and Munich (p<0.02, odds ratio 1.35 (confidence interval 1.1–4.5)) and those between Edinburgh and Leuven approached significance (p = 0.06).
Leuven334 (11.0%)163 (10.0%)139 (5.0%)79.319.51.2
Munich102 (7.0%)98 (9.0%)145 (4.0%)85.015.00
Edinburgh234 (10.3%)246 (6.8%)189 (8.8%)79.519.70.8