Table 1

 Criteria for urgent investigation of suspected upper gastrointestinal cancer under the National Health Service “two week rule”

Uncomplicated dyspepsia>55 y old with onset of dyspepsia within the last year or continuous symptoms since onset
Or
Alarm symptoms at any ageAny of the following:
Dysphagia
Anorexia
Vomiting
Weight loss
Anaemia
Or
Dyspepsia with high risk features at any ageAny of the following:
Family history of upper gastrointestinal cancer in >2 first degree relatives
Barrett’s oesophagus
Pernicious anaemia
Peptic ulcer surgery >20 y previously
Known dysplasia, intestinal metaplasia or atrophic gastritis