Comparison between patients with and without hepatitis C virus (HCV)-RNA negative strand in their peripheral blood mononuclear cells (PBMC)
| HCV replication in PBMC | p Value | ||
|---|---|---|---|
| Positive | Negative | ||
| Values are mean (95% confidence interval of the mean) or number. | |||
| BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGTP, gamma-glutamyl transpeptidase. | |||
| No of patients | 11 | 7 | |
| Sex (M/F) | 8/3 | 5/2 | 1.0 |
| Age (y) | 46.5 (40.1–52.8) | 44.4 (35.4–53.5) | 0.668 |
| BMI (kg/m2) | 26.0 (24.2–27.7) | 24.3 (24.3–25.3) | 0.083 |
| Estimated duration of abnormal liver function tests (months) | 41.4 (6.9–75.8) | 26.3 (3.5–49.0) | 0.236 |
| AST (IU/l) | 43.7 (21.4–66.0) | 25.7 (18.6–32.8) | 0.069 |
| ALT (IU/l) | 61.3 (22.8–99.8) | 43.1 (20.3–66.0) | 0.375 |
| GGTP (IU/l) | 147.4 (69.6–225.2) | 68.0 (39.5–96.5) | 0.052 |
| Liver | |||
| HCV-RNA positive strand (%) | 3.6 (1.0–6.2) | 3.9 (0.9–7.0) | 0.851 |
| HCV-RNA negative strand (%) | 2.2 (0.3–4.0) | 2.3 (1.4–3.3) | 0.866 |
| PBMC | |||
| HCV-RNA positive strand (%) | 4.2 (2.5–5.9) | 1.8 (1.3–2.2) | 0.009 |