Table 1

 Demographic, endoscopic, pH monitoring, histological, and ultrastructural data of the studied population (normal healthy controls, and gastro-oesophageal reflux disease patients with erosive oesophagitis (ERD) and those with a normal appearing oesophageal mucosa (NERD))

NormalNERDERD
TEM, transmission electron microscopy.
No of subjects91313
Sex (M/F)4/54/97/6
Age (y) (mean (SD)38.67 (17.36)41.62 (11.77)42.54 (13.33)
    [range][26–63][22–59][25–65]
% Time oesophageal pH <45.42 (1.1)9.1 (2.3)10.4 (1.9)
Endoscopy
    Normal9130
    A000
    B007
    C005
    D001
Histology
    Normal9138
    Mild005
    Moderate000
    Severe000
TEM value (mean (SD))0.54 (0.08)2.24 (0.53)2.39 (0.44)