Patient group | Total patients (n) | Patients with beneficial effect | Baseline (day –3 to 0) (mean (SD)) | Effect of treatment (treatment−baseline) (mean (SD)) | Effect at follow up (follow up−baseline) (mean (SD)) | |
---|---|---|---|---|---|---|
Patients: 16 short bowel syndrome (SBS) patients (11 with jejunostomy and five with colon in continuity) and five rechallenged patients (all with end jejunostomy). | ||||||
Patients Nos 03 and 20 did not complete the follow up study period. Patient No 03 had only 30% colon and was excluded from group 5 (patients with ⩾50% colon). | ||||||
R, patients rechallenged with the same dose divided in two injections—that is, 12R is the rechallenged patient No 12. | ||||||
Effect of treatment: paired t test; treatment versus baseline, *p<0.05. | ||||||
Effect at follow up: paired t test; follow up versus baseline, all non-significant (p>0.05). | ||||||
Body weight (kg) | 1. SBS patients | 16 | 11 | 58.4 (12.3) | 0.9 (2.1) | 0.4 (1.6) |
2. SBS patients with end jejunostomy | 10 | 7 | 60.7 (11.4) | 1.4 (2.6) | 0.6 (1.8) | |
3. SBS patients with ⩾50% colon | 5 | 3 | 57.6 (13.5) | 0.0 (0.6) | 0.1 (0.8) | |
4. SBS patients, high dietary compliance | 10 | 6 | 60.1 (13.0) | 0.1 (1.4) | −0.2 (1.1) | |
5. Rechallenged (1st treatment) | 5 | 4 | 60.8 (12.2) | 0.5 (1.7) | −0.5 (1.4) | |
6. Rechallenged (2nd treatment) | 5 | 5 | 60.1 (10.1) | 2.2 (1.1)* | 0.2 (1.2) |