Clinical evidence for a steatogenic effect for genotype 3
| HCV, hepatitis C virus; IR, insulin resistance. |
| • Hepatic steatosis is present in the majority of patients with genotype 3 infection |
| • Hepatic steatosis correlates with the level of HCV RNA in serum and the liver |
| • In patients infected with genotype 3 (but not genotype 1), successful viral clearance with antiviral therapy results in the disappearance of steatosis, only to recur on viral relapse |
| • IR has been observed to be less common among genotype 3 infected patients, even in those with extensive hepatic steatosis. |