| Author | Patients | Therapeutic intervention | Median follow up (years) | Number of biopsies | Persistence of intestinal metaplasia (%) | Development of dysplasia |
|---|---|---|---|---|---|---|
| *Targeted by methylene blue. †100% because intestinal metaplasia at follow up was inclusion criteria. ‡Unpublished. | ||||||
| De Meester100 | F | Fundoplication | 2.1 | 6 | 5 (33%) | Regression of inital dysplasia in onese |
| Goldstein48 | 85 | No data | 2.4 | 2 | 6 (7%) | None |
| Morales108 | 28 | No data | 2.5 | 2–4* | 19 (68%) | 1 (1.4% /year) |
| Sharma101 | 34 | No data | 2 | 4 | † | 1 (1.5%/year) |
| Peitz‡ | 19 | H pylori eradication, partly PPI | 2.5 | 3 | 8 (42%) | None |