Use of PPI | | | | | | | |
Never | 9387 (93.9) | 265 (92.3) | 1.00 (reference) | 173 (88.7) | 1.00 (reference) | 291 (89.0) | 1.00 (reference) |
Past | 214 (2.1) | 5 (1.7) | 0.81 (0.33–1.99)* | 8 (4.1) | 1.96 (0.94–4.07)* | 7 (2.1) | 1.02 (0.48–2.20)* |
Current (all durations) | 399 (4.0) | 17 (5.9) | 1.51 (0.91–2.50)* 0.84 (0.48–1.50)† | 14 (7.2) | 1.89 (1.08–3.32)* 1.06 (0.57–2.00)† | 29 (8.9) | 2.31 (1.55–3.44)* 1.75 (1.10–2.79)† |
Current <1 year | 246 (2.5) | 7 (2.4) | 1.05 (0.49–2.25)* 0.64 (0.28–1.42)† | 11 (5.6) | 2.51 (1.34–4.71)* 1.42 (0.72–2.81)† | 17 (5.2) | 2.17 (1.31–3.61)* 1.67 (0.96–2.90)† |
Current 1–3 years | 117 (1.2) | 8 (2.8) | 2.34 (1.12–4.89)* 1.22 (0.55–2.72)† | 3 (1.5) | 1.31 (0.41–4.21)* 0.72 (0.22–2.42)† | 8 (2.4) | 2.15 (1.03–4.47)* 1.61 (0.71–3.61)† |
Current >3 years | 36 (0.4) | 2 (0.7) | 1.78 (0.42–7.56)* 0.87 (0.20–3.87)† | 0 (0.0) | NA | 4 (1.2) | 3.89 (1.36–11.1)* 2.95 (0.97–8.97)† |
Use of H2 blockers | | | | | | | |
Never | 8335 (83.4) | 220 (76.7) | 1.00 (reference) | 147 (75.4) | 1.00 (reference) | 245 (74.9) | 1.00 (reference) |
Past | 763 (7.6) | 31 (10.8) | 1.54 (1.04–2.26)* | 19 (9.7) | 1.39 (0.86–2.27)* | 29 (8.9) | 1.26 (0.85–1.87)* |
Current (all durations) | 902 (9.0) | 36 (12.5) | 1.55 (1.08–2.22)* 1.20 (0.78–1.84)† | 29 (14.9) | 1.85 (1.23–2.79)* 1.06 (0.65–1.72)† | 53 (16.2) | 1.96 (1.44–2.66)* 1.41 (0.97–2.05)† |
Current <1 year | 413 (4.1) | 10 (3.5) | 0.92 (0.48–1.75)* 0.75 (0.38–1.48)† | 18 (9.2) | 2.48 (1.50–4.10)* 1.43 (0.81–2.52)† | 31 (9.5) | 2.47 (1.67–3.64)* 1.91 (1.23–2.95)† |
Current 1–3 years | 221 (2.2) | 8 (2.8) | 1.42 (0.69–2.93)* 1.03 (0.48–2.21)† | 5 (2.6) | 1.30 (0.52–3.20)* 0.73 (0.28–1.88)† | 10 (3.1) | 1.53 (0.80–2.92)* 1.06 (0.53–2.12)† |
Current >3 years | 268 (2.7) | 18 (6.3) | 2.68 (1.62–4.42)* 2.10 (1.20–3.68)† | 6 (3.1) | 1.33 (0.58–3.03)* 0.73 (0.30–1.76)† | 12 (3.7) | 1.50 (0.83–2.72)* 0.93 (0.48–1.80)† |