Use of PPI or H2 blockers combined |
Never | 8125 (81.2) | 213 (74.2) | 1.00 (reference) | 140 (71.8) | 1.00 (reference) | 234 (71.6) | 1.00 (reference) |
Past | 691 (6.9) | 26 (9.1) | 1.41 (0.93–2.15)* | 16 (8.2) | 1.32 (0.78–2.23)* | 20 (6.1) | 0.98 (0.61–1.56)* |
Current (all durations) | 1184 (11.8) | 48 (16.7) | 1.57 (1.14–2.17)* | 39 (20.0) | 1.93 (1.34–2.77)* | 73 (22.3) | 1.61 (1.12–2.30)* |
| | | 1.13 (0.75–1.72)† | | 1.09 (0.68–1.75)† | | 1.69 (1.19–2.41)† |
Current <1 year | 526 (5.3) | 11 (3.8) | 0.81 (0.44–1.50)* | 24 (12.3) | 2.69 (1.72–4.19)* | 37 (11.3) | 2.38 (1.61–3.33)* |
| | | 0.65 (0.34–1.26)† | | 1.54 (0.91–2.61)† | | 1.90 (1.26–2.88)† |
Current 1–3 years | 315 (3.2) | 11 (3.8) | 1.34 (0.72–2.49)* | 9 (4.6) | 1.63 (0.82–3.24)* | 16 (4.9) | 1.74 (1.03–2.93)* |
| | | 0.95 (0.47–1.85)† | | 0.88 (0.41–1.88)† | | 1.38 (0.77–2.47)† |
Current >3 years | 343 (3.4) | 26 (9.1) | 2.99 (1.95–4.59)* | 6 (3.1) | 1.03 (0.45–2.36)* | 20 (6.1) | 2.00 (1.24–3.20)* |
| | | 2.19 (1.30–3.70)† | | 0.53 (0.21–1.30)† | | 1.26 (0.71–2.23)† |