Table 2

 Target genes searched by viral insertion

CodeGene/type of sequenceFull name of gene and proteinFunction/protein family
ND, not determined.
Cancer associated genes
2A-1hTERTHuman telomerase reverse transcriptaseTelomerase regulation
2A-2TACC-1Transforming acedic coiled-coil containing protein 1Proto-oncogenes
5A-1IRF2Interferon regulatory factor 2Interferon regulation
7MUC16Mucin 16Transmembrane region and tyrosine phosphorylation site
11APDGFRBPlatelet derived growth factor receptor beta precursor; beta platelet derived growth factor receptorGrowth factor
37APCLAdenomatous polyposis coli-likeAPC homology
41GALiver mitochondrial glutaminase/breast cell glutaminaseGlutaminase proteins/proto-oncogene
F2T1-4MLL2Myeloid/lymphoid or mixed lineage leukaemia 2Transcriptional regulator
F2T1-5MGMTO-6-methylguanine-DNA methyltransferaseDNA reparation
54Tp84Nuclear matrix protein p84Nuclear matrix protein
83T-AhTERTHuman telomerase reverse transcriptaseTelomerase regulation
86TSERCA1Sarco/endoplasmic reticulum calcium ATPase 1Calcium regulation
GR2MAPK1Mitogen activated protein kinase 1Protein kinase
TAN7-3EVER2Epidermodysplasia verruciformis 2Integral membrane protein located in the ER
BB3hTERTHuman telomerase reverse transcriptaseTelomerase regulation
3T-470PDGFBPlatelet derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homologue)Growth factor
λYH16MLL4Myeloid/lymphoid or mixed lineage leukaemia 4Transcriptional regulator
Cellular genes
8AFN1Fibronectin 1Cell adhesion, morphology, and surface architecture
10ANEDD4LUbiquitin-protein ligase NEDD4-like; neural precursor cell expressed, developmentally downregulated gene 4-likeUbiquitin ligase
10SIRAK2Interleukin 1 receptor associated kinase 2Interleukin regulation
12A-1NCF1Neutrophil cytosolic factor 1NADPH oxidase
12A-2ITPR2Inositol 1,4,5-triphosphate receptor, type 2Calcium regulation
14CCTChaperonin containing TCP1, subunit 8 (theta)Cell cycle regulation
15TCEA3Transcription factor Sll related protein 4Binds to RNA polymerase II and stimulates nuclease activity
16ASCARA3Scavenger receptor class A, member 3Apoptotic regulation
100TRAP150Thyroid hormone associated protein 150 alphaCo-activator of nuclear receptor
101GCHFRGTP cyclohydrolase I feedback regulatory proteinKey enzyme of tetrahydrobiopterin biosynthesis
F2T2-5BIRC3Baculoviral IAP repeat-containing 3Apoptosis inhibitor
T2-6CHMLChoroideraemia-like (Rab escort protein 2)Geranylgeranylation of most Rab proteins
TN-2ORM1Orosomucoid 1Ubiquitin protein
TN-3BCL2L2BCL2-like 2Apoptotic regulation
TT-1RAI17Retinoic acid induced gene 17Co-regulator of androgen receptor
63TCASPR3Cell recognition molecule CASPR3Cell differentiation
77ThMCM8Human minichromosome maintenance protein 8Cell cycle regulation
83T-BSFXN5Sideroflexin 5Rab11-interacting protein
95TNTRK2Neutrophic tyrosine kinase receptor type 2Receptor for neurotrophic factor
FR2SMOC1SPARC related modular calcium binding 1Calcium regulation
GR1KIF3CKinesin family member 3CKinesin family
SA1ST3GAL IVAlpha2,3-sialyltransferaseCell differentiation
SA2IP3R 1Inositol triphosphate receptor type 1Calcium regulation
HC1707-1GRID2Glutamate receptor, ionotropic, delta 2Ionotropic glutamate receptor
MN3-3PDE6DPhosphodiesterase 6D, cGMP-specific, rod, deltaPhosphodiesterase
Unknown proteins
5A-2FLJ23027Hypothetical protein FLJ23027ND
9SLOC254277Similar to eukaryotic translation elongation factor 1 alpha 2Binding of aminoacyl-tRNAs to 80S ribosomes
13ALOC253820Similar to MEGF6 (Rattus norvegicus)EGF-like domain
43LOC402235Similar to Ac1147Rho-GEF protein and ligand for sAnk1
F2T2-1LOC169831Similar to Sorting nexin 7Receptor family with phox homology (PX) domain
F2T2-2LOC342193Similar to transcriptional co-repressor Sin3A; transcriptional regulator, SIN3A (yeast)Transcription of the gene encoding luteinising hormone receptor
TAT6-4LOC376426Similar to v-erb-a avian erythroblastic leukaemia viral oncogene homologue 2-likeProto-oncogene
FR3LOC222792Similar to 60S ribosomal protein L7A (Surfeit locus protein 3)ND
FR7FR7FR7 geneND
GR3LOC342670Similar to putative protein, nematode specific (Caenorhabditis elegans)ND
SA5LOC204740Similar to hypothetical protein DKFZp434F1017ND
669HbLOC116166Similar to sorbitol dehydrogenase (L-iditol 2-dehydrogenase)Catalyses the interconversion of polyols
PP5TLOC221026Similar to 60S ribosomal protein L17 (L23)ND
PP7TFLJ39630Hypothetical protein 1–107ND