Classification scheme | Descriptive statistics reporting CRP values among patients in three classification schemes | Results of polychotomous logistic regression, considering log [CRP] as predictor | Proportion of patients with Rutgeerts’ score of 0 or 1 (out of 5) (% (ratio)) | ||
---|---|---|---|---|---|
CRP (median (min, max)) | CRP (mean (SD)) | 2 degree of freedom tests of association with log [CRP] | OR (95% CI)† | ||
*For one way comparison of patients with a positive comb sign relative to those with mural hyperenhancement and no comb sign, p = 0.03. | |||||
†95% confidence interval (CI) not containing the value 1 indicates significant association with log CRP unadjusted for multiple comparison; OR, odds ratio. | |||||
‡For one way comparison of patients with increased fat density relative to those with mural enhancement and normal fat density, p = 0.002. | |||||
CT mural+, computed tomography finding of segmental mural hyperenhancement; CT mural−, absence of CT finding of mural hyperenhancement; comb+, CT findings of engorged vasa recta; comb−, normal appearance of perienteric vasculature; increased fat density+, CT findings of oedema/stranding in perienteric fat; increased fat density−, normal appearance of perienteric fat; endoscopy+, endoscopic findings of active Crohn’s disease, as outlined in materials and methods; endoscopy−, absence of endoscopic findings of active Crohn’s disease. | |||||
Perienteric inflammation v only mural inflammation or no inflammation | |||||
Comb+ (n = 29) | 0.58 (0.02,10.30) | 1.67 (2.57) | 0.07* | 1.0 (ref)* | 41% (12/29) |
CT mural+ comb− (n = 45) | 0.27 (0.02,23.70) | 1.28 (3.59) | 0.5 (0.2,0.9)* | 71% (32/45) | |
CT mural− comb− (n = 23) | 0.31 (0.02,5.07) | 0.70 (1.09) | 0.5 (0.2,1.0) | 91% (21/23) | |
Perienteric inflammation v only mural inflammation or no inflammation | |||||
Increased fat density+ (n = 22) | 0.96 (0.11,23.70) | 2.66 (5.16) | 0.005‡ | 1.0 (ref)‡ | 45% (10/22) |
CT mural+ increased fat density− (n = 51) | 0.23 (0.02,10.30) | 0.93 (1.72) | 0.3 (0.1,0.6)‡ | 67% (34/51) | |
CT mural− increased fat density− (n = 24) | 0.28 (0.02,5.07) | 0.68 (1.07) | 0.3 (0.1,0.7) | 88% (21/24) | |
No inflammation v mural inflammation without perienteric inflammation | |||||
CT mural− endoscopy− (n = 16) | 0.24 (0.02,5.07) | 0.73 (1.26) | 0.38 | 1.0 (ref) | 100% (16/16) |
CT mural+ endoscopy + increased fat density− comb sign− (N = 16) | 0.36 (0.02,3.41) | 0.78 (0.96) | 1.2 (0.4 −3.1) | 31% (5/16) | |
All other combinations (n = 65) | 0.40 (1.51,3.40) | 1.51 (3.40) | 1.6 (0.8,3.5) | 68% (44/65) |