Table 1

 Median (interquartile range) area under the curve values in placebo and antibiotic treated mice

PlaceboAntibiotic
0 mm Hg30 mm Hg60 mm Hg0 mm Hg30 mm Hg60 mm Hg
*p<0.05 and **p = 0.08 versus day 0; †p<0.05 versus placebo.
Day 00.21.21.70.20.71.3
(0.2–0.3)(0.6–1.3)(1.0–2.0)(0.2–0.6)(0.5–1.4)(1.0–2.0)
Day 100.21.12.20.41.6**2.8*†
(0.1–0.3)(0.5–1.4)(1.0–2.4)(0.1–0.6)(0.6–2.0)(2.0–3.1)
Day 300.30.71.60.41.02.1**
(0.2–0.4)(0.5–1.5)(1.4–2.3)(0.3–0.4)(0.5–1.5)(1.4–2.4)