Statistical evaluation of continuous indices according to intention to treat analysis
5-ASA | Azathioprine | p Value | ||||||
---|---|---|---|---|---|---|---|---|
n | Mean (SD) | Min-Max | n | Mean (SD) | Min-Max | Wilcoxon* | ANOVA† | |
AZA, azathioprine; 5-ASA, 5-aminosalicylic acid; PGA, physician global assessment. | ||||||||
*Wilcoxon test for each time; †analysis of variance for repeated measures. | ||||||||
Powell-Tuck index | ||||||||
Start | 36 | 8.7 (2.0) | 8.0–13.0 | 36 | 8.4 (1.4) | 8.0–11.0 | 0.4 | |
3 months | 36 | 2.8 (2.6) | 0.0–9.0 | 36 | 2.6 (4.3) | 0.0–23.0 | 0.1 | |
6 months | 36 | 2.7 (2.9) | 0.0–10.0 | 36 | 1.4–2.6 | 0.0–11.0 | 0.01 | 0.3 |
Baron index | ||||||||
Start | 36 | 2.6 (0.5) | 2.0–3.0 | 36 | 2.6 (0.5) | 2.0–3.0 | 0.6 | |
3 months | 36 | 2.3 (0.8) | 1.0–3.0 | 36 | 1.1 (1.2) | 0.0–3.0 | <0.0001 | |
6 months | 36 | 2.2 (1.0) | 0.0–3.0 | 36 | 0.9 (1.2) | 0.0–3.0 | <0.0001 | <0.001 |
PGA | ||||||||
Start | 36 | 5.2 (0.7) | 4.0–6.0 | 36 | 5.2 (0.8) | 3.0–6.0 | 0.8 | |
3 months | 36 | 4.6 (1.4) | 1.0–6.0 | 36 | 2.6 (1.8) | 1.0–6.0 | <0.0001 | |
6 months | 36 | 4.1 (1.8) | 1.0–6.0 | 36 | 2.6 (1.9) | 1.0–6.0 | 0.001 | <0.001 |