Biochemical data at diagnosis of primary biliary cirrhosis (PBC), at referral to the Royal Free Hospital, and at the last follow up, in 43 patients with PBC-systemic sclerosis (PBC-SSc), and 82 with PBC alone matched by serum bilirubin at referral to the Royal Free Hospital
| At diagnosis | At referral to Royal Free Hospital | At last follow up* | |
|---|---|---|---|
| Values are median (range). | |||
| *Values at the last follow up for patients alive, last values before transplantation for transplanted patients, and last values before death for patients who died. | |||
| †Bilirubin values used for matching the cohort of patients with PBC alone. | |||
| ‡Two sample t test with equal variances was done using log transformed values for comparison of the two cohorts. No significant differences were observed. | |||
| Bilirubin (μmol/l)‡ | |||
| PBC-SSc | 17 (4–109) | 13 (4–174)† | 15.5 (5–590) |
| PBC | 12 (2–120) | 13 (3–112) | 28 (5–438) |
| Albumin (g/l)‡ | |||
| PBC-SSc | 40.5 (29–49) | 41.5 (27–47) | 38.5 (27–47) |
| PBC | 41 (31–48) | 42 (27–49) | 40 (20–49) |
| Alkaline phosphatase (U/l)‡ | |||
| PBC-SSc | 334 (74–1038) | 291 (94–2090) | 247 (83–1694) |
| PBC | 403 (89–2300) | 282 (82–1039) | 249 (66–1009) |