Rate of advent of complications from referral through last follow up in 43 patients with primary biliary cirrhosis-systemic sclerosis (PBC-SSc) and 82 with PBC alone matched by serum bilirubin at referral to Royal Free Hospital
| Complication‡ | PBC-SSc (n = 43) | PBC (n = 82) |
|---|---|---|
| Values are number (%). | ||
| *p = 0.03 (Pearson χ2 test). | ||
| †p = 0.005 (Pearson χ2 test). | ||
| ‡Log rank test was done for comparison of time to occurrence of complications. No significant differences were observed. | ||
| New pruritus | 0 (0%) | 3 (4%) |
| New fatigue | 6 (14%) | 14 (17%) |
| Ankle oedema | 8 (19%) | 18 (22%) |
| Ascites | 5 (12%) | 15 (18%) |
| Oesophageal varices | 4 (9%) | 18 (22%) |
| Variceal bleeding | 4 (9%) | 6 (7%) |
| Upper gastrointestinal non-variceal bleeding | 3 (7%) | 4 (5%) |
| Spontaneous bacterial peritonitis | 4 (9%)* | 1 (1%)* |
| Portosystemic encephalopathy | 3 (7%) | 7 (9%) |
| Hepatocellular carcinoma | 0 (0%) | 2 (2%) |
| Septicaemia | 4 (9%)† | 0 (0%)† |