Table 2

 Hazard ratios (HR) and 95% confidence interval (95% CI) for colorectal cancer specific survival for all cases, the physically inactive, and the physically active, adjusted for stage (categorical), degree of differentiation (categorical), age and sex, per cent fat, and body mass index

HR (95% CI) comparing quartile of plasma level with quartile 1HR per increase of 1 SD in hormone level
Q2Q3Q4
Standard deviation (SD) for insulin-like growth factor 1 (IGF-1) is 8.5 nmol/l; SD for insulin-like growth factor binding protein 3 (IGFBP-3) is 26.2 nmol/l.
Quartiles are based on all 443 cases.
All cases
    IGF-1 per SD1.29 (0.80–2.08)1.17 (0.72–1.89)0.95 (0.58–1.55)0.95 (0.80–1.14) p = 0.59
    IGFBP-3 per SD0.86 (0.53–1.39)0.97 (0.61–1.56)0.70 (0.43–1.14)0.87 (0.74–1.03) p = 0.11
Physically inactive
    IGF-1per SD1.34 (0.74–2.45)1.06 (0.57–1.95)1.57 (0.86–2.84)1.13 (0.92–1.39) p = 0.24
    IGFBP-3 per SD1.07 (0.59–2.00)1.30 (0.71–2.36)1.26 (0.68–2.35)1.08 (0.88–1.33) p = 0.45
Physically active
    IGF-1per SD0.69 (0.28–1.68)0.89 (0.35–2.16)0.30 (0.11–0.81)0.59 (0.41–0.86) p = 0.006
    IGFBP-3 per SD0.42 (0.18–1.00)0.43 (0.18–1.04)0.17 (0.07–0.44)0.49 (0.33–0.77) p<0.001