Table 3

 Hazard ratios (HR) and 95% confidence interval (95% CI) for colorectal cancer (CRC) specific survival for all cases, the physically inactive, and the physically active, adjusted for stage (categorical), degree of differentiation (categorical), age and sex, per cent fat, BMI, and insulin-like growth factor 1/insulin-like growth factor binding protein 3 (IGF-1/IGFBP-3)

HR (95% CI) comparing quartile of plasma level with quartile 1HR per increase of 1 SD in hormone level
Q2Q3Q4
Standard deviation (SD) for IGF-1 is 8.5 nmol/l; SD for IGFBP-3 is 26.2 nmol/l.
Quartiles are based on all 443 cases.
All cases
    IGF-1 per 8.5 nmol/l1.29 (0.80–2.08)1.16 (0.71–1.90)1.10 (0.62–1.94)1.01 (0.89–1.14) p = 0.90
    IGFBP-3 per 26.2 nmol/l0.87 (0.53–1.42)0.99 (0.60–1.64)0.72 (0.41–1.24)0.87 (0.71–1.06) p = 0.16
Physically inactive
    IGF-1per 8.5 nmol/l1.28 (0.70–2.34)0.93 (0.49–1.75)1.36 (0.67–2.75)1.08 (0.85–1.37); p = 0.54
    IGFBP-3 per 26.2 nmol/l1.04 (0.56–1.92)1.22 (0.64–2.33)1.17 (0.59–2.32)1.04 (0.82–1.32); p = 0.73
Physically active
    IGF-1per 8.5 nmol/l0.84 (0.35–2.02)1.36 (0.52–3.53)0.90 (0.28–2.85)0.90 (0.55–1.45); p = 0.65
    IGFBP-3 per 26.2 nmol/l0.48 (0.19–1.19)0.50 (0.20–1.28)0.23 (0.08–0.73)0.52 (0.33–0.83); p = 0.006