Table 1

 Inactive* variants of p57–73 QE65 with a single amino acid substitution

SubstitutionAgonist (%)SubstitutionAgonist (%)
* Interferon γ ELISPOT response not significantly different from medium alone (Student’s t test); n = 8.
Values are mean (SEM).
65E→P−0.05 (3.5)64P→Q3.2 (5.21)
65E→Y0.47 (1.23)67P→Y3.21 (2.63)
66L→R1.29 (2.05)65E→T3.36 (4.53)
64P→K1.58 (1.79)66L→E3.53 (4.18)
65E→K2.01 (1.77)66L→K4.36 (3.12)
67P→K2.96 (2.11)64P→M4.56 (5.36)