Table 2

 Apolipoprotein E (APOE) genotype distribution in patients with spontaneously resolved infection (HCV RNA negative cleared infection) versus chronic infection (HCV RNA positive chronic infection)

APOE genotypeChronic HCV infection (n = 312)Cleared HCV infection (n = 108)GRR (95% CI)p Value
Values are number (%).
HCV, hepatitis C virus; GRR, genotype relative risk; 95% CI, 95% confidence interval.
E2,E2 00
E2,E3 23 (7.5%)16 (15%)0.36 (0.18–0.73)0.005
E2,E4 4 (1%)5 (4%)0.20 (0.52–0.77)0.020
E3,E3 210 (67.5%)53 (49%)1
E3,E4 72 (23%)33 (31%)0.55 (0.33–0.92)0.022
E4,E4 3 (1%)1 (1%)0.76 (0.77–7.42)NS