Table 1

 Primary outcomes

OutcomenBaseline1 year
Values are mean (SD).
†p values for significance (at alpha = 0.05) are based on Holm’s modified Bonferroni method.32
*Statistically significant result
GP visits (primary outcome)
    Control group1362.75 (1.36)2.26 (2.04)Guidebook effect: −1.56 (−1.98, −1.15); p<0.001* (p<0.017)† Self-help group effect: 0.00 (−0.28, 0.28); p = 0.990 (p>0.05)†
    Guidebook group1413.69 (2.41)1.03 (1.60)
    Guidebook and self-help group1383.51 (2.27)0.96 (1.42)
Global impressions scale—severity
    Control group1173.29 (0.88)3.93 (1.31)Guidebook effect: 0.25 (−0.05, 0.56); p = 0.102 (p>0.05)† Self-help group effect: −0.14 (−0.49, 0.21); p = 0.433 (p>0.017)†
    Guidebook group1253.14 (0.84)4.15 (1.41)
    Guidebook and self-help group1223.23 (0.98)4.03 (1.33)
Global impressions scale—change
    Control group117NA4.63 (1.41)Guidebook effect: 0.51 (0.23, 0.79); p = 0.001* (p<0.025)† Self-help group effect: −0.09 (−0.38, 0.21); p = 0.559 (p>0.025)†
    Guidebook group125NA5.14 (1.20)
    Guidebook and self-help group122NA5.06 (1.27)