Table 6

 Multivariate analysis of overall survival and disease free survival in patients with locally advanced non-metastatic colorectal cancer

Overall survival (Hazard ratio* (95% CI))p ValueDisease free survival (Hazard ratio* (95% CI))p Value
*Adjusted for age, sex, and tumour, node, metastases (TNM) stage (Cox proportional hazards regression).
95% CI, 95% confidence interval; MMR, mismatch repair.
MMR status (deficient/competent)1.02 (0.49–2.13)0.9611.22 (0.67–2.22)0.508
Adjuvant chemotherapy (yes/no)1.88 (1.13–3.12)0.0151.54 (1.04–2.29)0.031
MMR status×chemotherapy1.81 (1.13–2.92)0.0141.68 (1.15–2.44)0.007