Anxiety and depression levels during treatment with citalopram or placebo, assessed using the hospital anxiety and depression scale (HAD) and symptom checklist-90-revised (SCL-90R)
| Before citalopram | Citalopram 3 weeks | Citalopram 6 weeks | Before placebo | Placebo 3 weeks | Placebo 6 weeks | |
|---|---|---|---|---|---|---|
| *Significant compared with run in: p<0.05. | ||||||
| †Significant compared with placebo: p<0.05. | ||||||
| Anxiety (HAD) | 11.4 (1.1) | 10.7 (1.0)*† | 9.6 (0.8)*† | 13.1 (0.9) | 12.4 (1.0)* | 11.0 (1.1)* |
| Depression (HAD) | 6.0 (0.9) | 3.8 (0.6)*† | 3.7 (0.7)*† | 6.3 (1.0) | 6.3 (0.9) | 6.0 (0.9) |
| Anxiety (SCL-90R) | 17.7 (1.8) | 15.5 (1.6) | 14.9 (1.6) | 16.8 (1.8) | 16.4 (1.8) | 16.3 (1.9) |
| Depression (SCL-90R) | 31.5 (3.3) | 29.1 (2.8) | 28.6 (2.9) | 31.2 (3.3) | 32.0 (3.2) | 30.1 (3.3) |