Table 7

 Current indications for referral of adults to an intestinal transplantation centre in the UK

Complications of parenteral nutrition
• Liver disease (portal hypertension, bridging hepatic fibrosis, or cirrhosis) due to parenteral nutrition—irreversible despite referral and management by an established parenteral nutrition centre.
• Progressively compromised vascular access for parenteral feeding—loss of all but two major venous access points (one of which should be above the diaphragm).
• Recurrent or life threatening central line sepsis (including fungal sepsis).
• Inadequate maintenance on parenteral nutrition for any other reason—for instance, inability to manage hydration/nutrition status despite parenteral nutrition.
High risk conditions
• Requirement for extensive evisceration (that is, desmoid tumours, trauma, rare selected malignancies including neuroendocrine tumours)