Table 3 Multivariate analysis for CARD15 and CARD4 variants (logistic regression)

	gASCA positivity	Ileal involvement	Colonic involvement	Anal involvement
CARD15	0.005	0.008	NS	0.029
> 1 variant	OR 1.58	OR 1.77		OR 0.69
	95% CI 1.15 to 2.18	95% CI 1.16 to 2.70		95% CI 0.50 to 0.96
CARD4 indel	0.009	NS	0.007	NS
> 1 variant	OR 1.48		OR 1.57
	95% CI 1.10 to 1.98		95% CI 1.13 to 2.18

CARD, Caspase recruitment domain; gASCA, anti-S. cerevisiae antibodies. P value, OR and 95% CI are indicated.