Intravenous antioxidant regimen: protocol for use of selenium, ascorbic acid and n-acetycysteine
| Selenium in 50 ml normal saline (dose as elemental selenium) |
| Day 1: 1000 μg selenium over 24 hours intravenously |
| Day 2: 400 μg selenium over 24 hours intravenously |
| Day 3: 200 μg selenium over 24 hours intravenously, (continued for up to day 7) |
| Ascorbic acid in 100 ml normal saline |
| Day 1: 2000 mg over 24 hours intravenously |
| Day 2: 2000 mg over 24 hours intravenously |
| Day 3: 1000 mg over 24 hours intravenously (continued for up to day 7) |
| n-Acetylcysteine |
| Day 1: 300 mg/kg over 24 hours intravenously |
| Day 2: 150 mg/kg over 24 hours intravenously |
| Day 3: 75 mg/kg over 24 hours intravenously (continued for up to day 7) |