History of gluten-free diet and clinical features of coeliac patients diagnosed in childhood, maintained on a normal diet until adulthood
| Total cohort (n = 61) | Latent (n = 13) | Silent (n = 48) | p Value latent vs silent | |
|---|---|---|---|---|
| Latent, patients with no atrophy; silent, patients with villous atrophy. | ||||
| BMI, body mass index; F, female; GFD, gluten-free diet; M, male; ND, normal diet; NS, non-significant. | ||||
| Gender (M/F) | 23/38 | 4/9 | 19/29 | NS |
| Age of diagnosis (first GFD introduction): median (range), months | 17 (6–192) | 13 (6–27) | 19 (6–192) | <0.05 |
| History of GFD | ||||
| Duration of the first GFD: median (range), years | 4 (1–18) | 3.9 (2–12) | 4.5 (1–18) | NS |
| Total duration of GFD: median (range), years | 7 (1–21) | 6.5 (2–17) | 8 (1–18) | NS |
| Duration of ND before evaluation: median (range), years | 10 (2–44) | 14 (2–30) | 14 (2–44) | NS |
| Evaluation at adulthood | ||||
| Age at evaluation: median (range), years | 26 (17–53) | 25 (18–33) | 26 (18–53) | NS |
| Current gluten consumption: mean±SD, g/day | 8±4 | 8±3 | 8.6±5 | NS |
| No. (%) of patients with mild clinical symptoms | 29 (47%) | 5 (40%) | 24 (50%) | NS |
| BMI (mean±SD), kg/m2 | 21.4±3 | 21.4±2 | 21.4±3 | NS |