Investigations performed in study participants
| Healthy | D-IBS | |
|---|---|---|
| Upper endoscopy was performed only in patients experiencing dyspepsia. In four of the D-IBS patients a colonoscopy and biopsy were performed showing <20 CD3+ cells/100 surface epithelial cells, excluding lymphocytic colitis. | ||
| Upper endoscopy | 0 | 14/20 |
| Colonoscopy and biopsy | 0 | 4/20 |
| Jejunal biopsy and aspirate | 14/14 | 20/20 |
| Blood biochemical profile | 14/14 | 20/20 |
| Coeliac serology and thyroid function | 0 | 20/20 |
| Stool culture and microscopy | 0 | 20/20 |
| Skin prick tests | 14/14 | 20/20 |
| Abdominal imaging (barium, sonography, tomography) | No | 12/20 |