Table 4 Risk of oesophageal and gastric cancer by height at baseline in the Netherlands Cohort Study on Diet and Cancer, 1986–1999*
Histological subtypes of the oesophagusAdenocarcinoma in sub sites of the stomach
Squamous cell carcinomaAdenocarcinomaCardiaDistant stomachNOS
Cases/person time at risk (years)RR† (95% CI)Cases/person time at risk (years)RR‡ (95% CI)Cases/person time at risk (years)RR‡ (95% CI)Cases/person time at risk (years)RR§ (95% CI)Cases/person time at risk (years)RR†† (95% CI)
Height at baseline (cm)
M: <17020/64411.0 (Referent)19/73061.0 (Referent)13/73061.0 (Referent)37/72371.0 (Referent)28/72371.0 (Referent)
F: <160
M: 170–17415/112100.41 (0.20 to 0.82)37/121511.15 (0.65 to 2.04)37/121511.64 (0.86 to 3.13)71/120751.18 (0.78 to 1.78)42/120750.85 (0.51 to 1.40)
F: 160–164
M: 175–17929/141100.67 (0.36 to 1.23)36/152480.98 (0.55 to 1.73)44/152481.71 (0.90 to 3.23)73/150641.06 (0.70 to 1.60)49/150640.91 (0.55 to 1.50)
F: 165–169
M: 180–18417/82340.57 (0.27 to 1.20)21/90760.88 (0.46 to 1.67)34/90762.01 (1.05 to 3.86)42/89880.94 (0.59 to 1.50)32/89880.89 (0.52 to 1.51)
F: 170–174
M: ⩾1855/42550.37 (0.13 to 1.08)11/45400.86 (0.40 to 1.85)17/45401.85 (0.88 to 3.92)12/45290.54 (0.27 to 1.08)22/45291.30 (0.71 to 2.39)
F: ⩾175
p trend¶ =  0.22p trend  =  0.40p trend  =  0.06p trend  =  0.07p trend  =  0.52
Continuous, 5 cm increments86/442490.90 (0.74 to 1.11)124/483210.95 (0.83 to 1.08)145/483211.07 (0.95 to 1.21)235/478930.92 (0.83 to 1.01)173/478931.03 (0.90 to 1.18)
  • *RR, rate ratio; CI, confidence interval; NOS, adenocarcinoma of the stomach, not otherwise specified; M, males; F, females. The first year of follow-up was excluded from the analyses. Case-cohort analyses were used, which means that the cases were identified from the entire cohort, while the person years were based only on the subcohort.

  • †Rate ratios adjusted for age; sex; BMI at baseline (kg/m2); current smoking (yes/no); number of cigarettes/day; and number of years of smoking; alcohol intake (g/day); and fruit consumption (g/day).

  • ‡Rate ratios adjusted for age; sex; BMI at baseline (kg/m2); current smoking (yes/no); number of cigarettes/day; and number of years of smoking.

  • §Rate ratio adjusted for age; sex; BMI at baseline (kg/m2); current smoking (yes/no); number of cigarettes/day; number of years of smoking; and highest level of education (primary school, lower vocational school, high school and higher vocational/university).

  • ††Rate ratio adjusted for age; sex; BMI at baseline (kg/m2); current smoking (yes/no); number of cigarettes/day; number of years of smoking; highest level of education (primary school, lower vocational school, high school and higher vocational/university); and a history of gastric ulcer or bleeding (yes/no).

  • ¶Tests for dose-respond trends were assessed by fitting ordinal variables as continuous terms in the Cox proportional hazard model. p Trends were calculated for all categories of a variable. The reported p values are two sided.