Dose (mg/day) | Pre-treatment,mean±SD | Post-treatment,mean±SD | Change (%),median (range) | |
ALT (IU/l) | 150 | 109.2±49.7 | 95.8±60.2 | −15.3 (−80.7 to +375.9) |
600 | 106.3±59.4 | 75.7±41.9 | −29.2 (−88.3 to +95.2) | |
900 | 110.6±57.3 | 81.3±90.5 | −36.2 (−81.4 to +1696.9) | |
AST (IU/l) | 150 | 84.0±39.1 | 75.5±43.6 | −13.6 (−74.2 to +347.2) |
600 | 82.4±41.8 | 63.1±32.9 | −25.0 (−82.7 to +72.5) | |
900 | 85.2±45.0 | 65.5±49.6 | −29.8 (−79.0 to +1026.1) | |
GGT (IU/l) | 150 | 87.5±73.0 | 70.4±58.3 | −22.4 (−74.6 to +145.9) |
600 | 82.4±62.2 | 49.7±43.0 | −41.0 (−81.1 to +153.1) | |
900 | 85.9±66.3 | 43.8±44.8 | −50.0 (−80.1 to +213.9) |