Table 5 Composition of serum bile acid in patients with chronic hepatitis C treated with UDCA
Dose (mg/day)Before treatmentAfter treatmentp Value
Total bile acid concentration (μmol/l)1508.63±9.7613.69±19.28<0.001
6009.42±12.0421.89±24.20<0.001
9009.17±9.3028.74±39.78<0.001
Cholic acid (%)15017.69±10.3311.35±7.08<0.001
60017.75±10.355.93±4.53<0.001
90018.15±9.545.14±4.19<0.001
Deoxycholic acid (%)15021.62±16.2413.84±11.39<0.001
60019.86±16.846.50±7.06<0.001
90018.74±15.295.68±6.58<0.001
Chenodeoxycholic acid (%)15054.46±14.1239.93±11.61<0.001
60055.37±13.9524.66±10.01<0.001
90055.95±13.6523.31±12.72<0.001
Ursodeoxycholic acid (%)1505.93±8.7234.25±13.75<0.001
6006.70±9.7262.26±13.69<0.001
9006.83±10.665.12±16.84<0.001
Lithocholic acid (%)1500.30±0.990.62±1.660.010
6000.33±1.230.66±1.350.010
9000.33±1.120.75±1.490.001
  • Data are expressed as mean±SD. The p values refer to paired t test (before vs after treatment).