Standardised incidence ratios (SIRs) and their 95% CIs for oesophageal cancer by histology among non-operated patients with duodenal ulcer, by follow-up duration, sex, presence of complications and calendar year of index hospitalisation*
| Adenocarcinoma | Squamous cell carcinoma | |||
|---|---|---|---|---|
| Number of cases | SIR (95% CI) | Number of cases | SIR (95% CI) | |
| *First year of follow-up was excluded. | ||||
| †Including bleeding and perforation. | ||||
| Overall | 27 | 1.7 (1.1–2.5) | 44 | 1.3 (0.96–1.8) |
| Follow-up duration, years | ||||
| 2–10 | 17 | 1.9 (1.1–3.1) | 33 | 1.6 (1.1–2.2) |
| 11+ | 10 | 1.5 (0.7–2.8) | 11 | 0.9 (0.5–1.6) |
| p for trend | 0.15 | 0.01 | ||
| Sex | ||||
| Men | 23 | 1.7 (1.1–2.5) | 34 | 1.3 (0.9–1.8) |
| Women | 4 | 2.1 (0.6–5.5) | 10 | 1.5 (0.7–2.7) |
| Complication† | ||||
| Yes | 12 | 1.2 (0.6–2.1) | 30 | 1.4 (0.95–2.0) |
| No | 15 | 2.6 (1.5–4.3) | 14 | 1.2 (0.6–2.0) |
| Calendar year of index hospitalisation | ||||
| 1965–79 | 10 | 2.1 (1.0–3.8) | 18 | 1.3 (0.8–2.1) |
| 1980–2003 | 17 | 1.6 (0.9–2.5) | 26 | 1.3 (0.9–2.0) |
| Age at entry | ||||
| <50 | 6 | 2.4 (0.9–5.1) | 9 | 2.0 (0.9–3.8) |
| 50–69 | 15 | 1.9 (1.1–3.1) | 25 | 1.4 (0.9–2.1) |
| 70– | 6 | 1.2 (0.4–2.5) | 10 | 0.9 (0.4–1.6) |
| p for trend | 0.09 | <0.001 | ||
| Calendar year of follow-up | ||||
| 1965–94 | 13 | 2.3 (1.2–4.0) | 25 | 1.2 (0.8–1.8) |
| 1995–2003 | 14 | 1.4 (0.8–2.3) | 19 | 1.5 (0.9–2.3) |