Echocardiographic and haemodynamic measures obtained in 16 healthy subjects and in 32 patients with cirrhosis
Variable | Healthy subjects (n = 16) | Patients with cirrhosis (n = 32) | p Value |
---|---|---|---|
E/A, early maximal ventricular filling velocity/late filling velocity; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; LVEF, left ventricular ejection fraction; RVSP, right ventricular systolic pressure; SVR, systemic vascular resistance. | |||
Mean arterial pressure (mm Hg) | 98 (2) | 85 (2) | <0.001 |
Heart rate (bpm) | 66 (3 | 73 (2) | 0.07 |
LVEDV (ml) | 89 (5) | 94 (6) | 0.94 |
LVESV (ml) | 30 (3) | 34 (3) | 0.91 |
LVEF (%) | 66 (3) | 66 (2) | 0.61 |
Stroke volume (ml) | 59 (3) | 61 (3) | 0.85 |
Cardiac output (l/min) | 4.0 (0.3) | 4.4 (0.2) | 0.29 |
E/A ratio | 1.15 (0.06) | 0.97 (0.05) | 0.04 |
Deceleration time (ms) | 191 (7) | 234 (8) | 0.001 |
RVSP (mm Hg) | 19 (1) | 23 (1) | 0.07 |
SVR (dyne s/cm5 m2) | 2094 (166) | 1639 (77) | 0.01 |