Comparison of patients with and without diastolic dysfunction at 28 days after transjugular intrahepatic portosystemic shunt implantation
| Variables | Before TIPS | After TIPS (%) | ||||
|---|---|---|---|---|---|---|
| Group 1 (E/A <1) | Group 2 (E/A >1) | p Value | Group 1 (E/A <1) | Group 2 (E/A >1) | p Value | |
| E/A, early maximal filling velocity/late filling velocity; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; LVEF, left ventricular ejection fraction; RVSP, right ventricular systolic pressure; SVR, systemic vascular resistance; TIPS, transjugular intrahepatic portosystemic shunt. | ||||||
| Baseline haemodynamic measures and the relative post-TIPS percentage changes. | ||||||
| Mean arterial pressure (mm Hg) | 79 (4) | 87 (2) | 0.06 | +10 (4) | +1 (3) | 0.13 |
| Heart rate (bpm) | 73 (5) | 73 (3) | 0.79 | +11 (4) | +9 (5) | 0.90 |
| LVEDV (ml) | 99 (13) | 92 (5) | 0.84 | +22 (11) | +22 (5) | 0.89 |
| LVESV (ml) | 36 (6) | 32 (4) | 0.57 | +69 (27) | +38 (15) | 0.42 |
| LVEF (%) | 65 (3) | 66 (2) | 0.76 | −11 (6) | 0 (3) | 0.046 |
| Stroke volume (mL) | 63 (7) | 60 (3) | 0.85 | +6 (9) | +22 (6) | 0.15 |
| Cardiac output (l/min) | 4.0 (0.4) | 4.6 (0.2) | 0.18 | +32 (9) | +29 (5) | 0.87 |
| E/A ratio | 0.87 (0.10) | 1.02 (0.05) | 0.14 | +11 (13) | +40 (15) | 0.22 |
| Deceleration time (ms) | 227 (14) | 238 (11) | 0.73 | +8 (11) | −12 (4) | 0.043 |
| RVSP (mm Hg) | 22 (2) | 24 (2) | 0.59 | +21 (15) | +16 (14) | 0.53 |
| SVR (dyne s/cm5 m2) | 1713 (171) | 1606 (82) | 0.68 | −13 (7) | −20 (4) | 0.36 |