Characteristic | Fatty liver alone | NASH stage 0 | NASH stage 1–2 | NASH stage 3–4 | p Value |
Age (years) | 47 (11) | 46 (11) | 47 (11) | 55 (11) | <0.001 |
Body mass index (kg/m2) | 32 (5) | 33 (6) | 33 (6) | 35 (7) | <0.001 |
⩾30 | 77 (66%) | 40 (80%) | 211 (73%) | 114 (79%) | |
Female | 62 (39%) | 26 (36%) | 210 (53%) | 123 (63%) | <0.001 |
Ethnicity | |||||
Caucasian | 79 (52%) | 34 (69%) | 190 (70%) | 92 (83%) | <0.001 |
African–American | 17 (11%) | 4 (8%) | 8 (3%) | 5 (4%) | |
Hispanic | 54 (35%) | 11 (2%) | 65 (24%) | 12 (11%) | |
Asian Pacific Islander | 3 (2%) | 0 (0) | 8 (3%) | 2 (2%) | |
Hypertension | 73 (47%) | 41 (70%) | 177 (61%) | 100 (69%) | <0.001 |
Diabetes | 23 (15%) | 15 (23%) | 115 (34%) | 106 (60%) | <0.001 |
Alanine aminotransferase (ALT) (U/l) | 68 (37) | 80 (37) | 92 (72) | 67 (44) | <0.001 |
Aspartate aminotransferase (AST) (U/l) | 42 (19) | 47 (20) | 62 (44) | 70 (45) | <0.001 |
AST/ALT ratio | 0.7 (0.3) | 0.6 (0.3) | 0.8 (0.3) | 1.2 (0.5) | <0.001 |
QUICKI | 0.318 (0.029) | 0.295 (0.026) | 0.303 (0.030) | 0.293 (0.020) | <0.001 |
Hyperlipidaemia | |||||
Neg | 103 (65%) | 33 (51%) | 179 (52%) | 109 (66%) | 0.002 |
Pos | 55 (35) | 32 (49%) | 166 (48%) | 55 (34%) |
QUICKI, quantitative assessment check index.