| Characteristic | NAFLD and fibrosis 0–2 n (%) | Fibrosis 3–4 n (%) | p Value | OR (95% CI) |
| Age ⩾50 years | 278 (45) | 133 (69) | <0.001 | 2.7 (1.9 to 3.8) |
| Subset 1 | 147 (45) | 67 (70) | <0.001 | 2.8 (1.7 to 4.6) |
| Subset 2 | 131 (44) | 66 (67) | <0.001 | 2.6 (1.6 to 4.2) |
| Female gender | 298 (48) | 123 (63) | <0.001 | 1.9 (1.3 to 2.6) |
| Subset 1 | 160 (49) | 58 (60) | 0.042 | 1.6 (1.0 to 2.6) |
| Subset 2 | 138 (47) | 65 (66) | 0.001 | 2.2 (1.4 to 3.6) |
| Body mass index ⩾28 kg/m2 | 385 (85) | 134 (93) | 0.01 | 2.4 (1.2 to 4.8) |
| Subset 1 | 206 (86) | 68 (94) | 0.05 | 2.7 (0.9 to 7.9) |
| Subset 2 | 180 (83) | 67 (92) | 0.06 | 2.3 (0.9 to 5.6) |
| HTN | 291 (58) | 100 (69) | 0.010 | 1.7 (1.1 to 2.5) |
| Subset 1 | 139 (53) | 44 (64) | 0.110 | 1.5 (0.9 to 2.7) |
| Subset 2 | 152 (62) | 56 (75) | 0.04 | 1.8 (1.0 to 3.2) |
| Diabetes | 153 (27) | 106 (60%) | <0.001 | 4.0 (2.8 to 5.7) |
| Subset 1 | 73 (24) | 52 (60) | <0.001 | 4.7 (2.8 to 7.8) |
| Subset 2 | 80 (30) | 54 (59) | <0.001 | 3.4 (2.0 to 5.5) |
| QUICKI <0.294 | 89 (30) | 24 (53) | 0.002 | 2.7 (1.4 to 5.0) |
| Subset 1 | 49 (29) | 15 (60) | 0.002 | 3.6 (1.5 to 8.6) |
| Subset 2 | 40 (31) | 11 (55) | 0.198 | 1.9 (0.7 to 4.8) |
| QUICKI<0.35 | 267 (90%) | 45 (100%) | 0.02 | * |
| Subset 1 | 150 (89%) | 25 (100%) | 0.09 | |
| Subset 2 | 117 (90%) | 20 (100%) | 0.12 | |
| HbA1c ⩾6.0% | 148 (43) | 67 (58) | 0.005 | 1.8 (1.2 to 2.7) |
| Subset 1 | 69 (41) | 35 (58) | 0.010 | 2.0 (1.1 to 3.7) |
| Subset 2 | 79 (45) | 32 (57) | 0.120 | 1.6 (0.9 to 2.9) |
| Hyperlipidaemia | 253 (45) | 55 (36) | 0.010 | 0.6 (0.4 to.9) |
| Subset 1 | 131 (44) | 26 (31) | 0.040 | 0.6 (0.3 to.9) |
| Subset 2 | 122 (46) | 29 (36) | 0.110 | 0.7 (0.4 to 1.1) |
| AST/ALT ⩾0.8 | 153 (26) | 141 (76) | <0.001 | 9.3 (6.3 to 13.6) |
| Subset 1 | 84 (27) | 72 (79) | <0.001 | 10.4 (5.9 to 18.3) |
| Subset 2 | 69 (25) | 69 (73) | <0.001 | 8.4 (5.0 to 14.4) |
*OR for QUICKI <0.350, not calculable.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CI, confidence interval; HTN, hypertension; OR, odds ratio; QUICKI, quantitative assessment check index.