Table 5 Effect on of bile acids in weakly acidic (pH 5.0) solutions on the permeability of rabbit oesophageal mucosa to fluorescein

		Glycolcholic acid (mmol/l)			Taurodeoxycholic acid (mmol/l)			Deoxycholic acid (mmol/l)
	Control (n = 11, N = 10)	0.5 (n = 11, N = 6)	2 (n = 16, N = 8)	5 (n = 8, N = 4)	0.5 (n = 8, N = 4)	2 (n = 8, N = 4)	5 (n = 10, N = 5)	0.5 (n = 12, N = 8)	2 (n = 14, N = 7)	5 (n = 12, N = 9)
ANOVA permeability curve, p		0.954	0.087	0.079	0.013	<0.0001	<0.0001	0.085	0.015	<0.0001
Permeability at 120 min (nmol/cm²)	0.36 (0.11)	0.36 (0.10)	0.58 (0.18)	0.68 (0.37)	0.70 (0.20)*	0.99 (0.25)***	2.24 (0.87)**	0.57 (0.14)	1.33 (0.65)	2.94 (0.74)***

Results for permeability at 120 min are given as mean (SEM).
*p<0.05 vs control (solution without the bile acid), **p<0.01 vs control, ***p<0.001 vs control.
N, number of animals; n, number of observations.